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SRPK2 Promotes Leukemia Cell Proliferation by Phosphorylating Acinus and Regulating Cyclin A1

SRPK, a family of cell cycle regulated protein kinases, phosphorylate Serine/Arginine (SR) domain-containing proteins in nuclear speckles and mediate the pre-mRNA splicing. However, the physiological roles of this event in cell cycle are incompletely understood. Here we show that SRPK2 binds and pho...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Jang, Sung-Wuk, Yang, Seung-ju, Ehlén, Åsa, Dong, Shaozhong, Khoury, Hanna, Chen, Jing, Persson, Jenny L., Ye, Keqiang
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805021/
https://ncbi.nlm.nih.gov/pubmed/18559500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0021
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