Active human immunodeficiency virus protease is required for viral infectivity.

Retroviral proteins are synthesized as polyprotein precursors that undergo proteolytic cleavages to yield the mature viral proteins. The role of the human immunodeficiency virus (HIV) protease in the viral replication cycle was examined by use of a site-directed mutation in the protease gene. The HI...

Full description

Saved in:
Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kohl, N E, Emini, E A, Schleif, W A, Davis, L J, Heimbach, J C, Dixon, R A, Scolnick, E M, Sigal, I S
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1988
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280500/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3290901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4686
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items