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Active human immunodeficiency virus protease is required for viral infectivity.

Retroviral proteins are synthesized as polyprotein precursors that undergo proteolytic cleavages to yield the mature viral proteins. The role of the human immunodeficiency virus (HIV) protease in the viral replication cycle was examined by use of a site-directed mutation in the protease gene. The HI...

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Detalhes bibliográficos
Main Authors: Kohl, N E, Emini, E A, Schleif, W A, Davis, L J, Heimbach, J C, Dixon, R A, Scolnick, E M, Sigal, I S
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC280500/
https://ncbi.nlm.nih.gov/pubmed/3290901
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