Functional genetic polymorphisms in the aromatase gene CYP19 vary the response of breast cancer patients to neoadjuvant therapy with aromatase inhibitors

Aromatase (CYP19) is a critical enzyme for estrogen biosynthesis, and aromatase inhibitors (AIs) are established endocrine therapy for post-menopausal women with breast cancer. DNA samples were obtained from 52 women pre- and post-AI treatment in the neoadjuvant setting. 82 breast cancer and 19 norm...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Wang, Liewei, Ellsworth, Katarzyna A., Moon, Irene, Pelleymounter, Linda L., Eckloff, Bruce W., Martin, Yvette N., Fridley, Brooke L., Jenkins, Gregory D., Batzler, Anthony, Suman, Vera J., Ravi, Saranya, Dixon, J. Michael, Miller, William R., Wieben, Eric D., Buzdar, Aman, M.Weinshilboum, Richard, Ingle, James N.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804935/
https://ncbi.nlm.nih.gov/pubmed/20048079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3224
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars