Increased Proliferation but Decreased Steroidogenic Capacity in Leydig Cells from Mice Lacking Cyclin-Dependent Kinase Inhibitor 1B

Proliferating cells express cyclins, cell cycle regulatory proteins that regulate the activity of cyclin-dependent kinases (CDKs). The actions of CDKs are regulated by specific inhibitors, the CDK inhibitors (CDKIs), which are comprised of the Cip/Kip and INK4 families. Expression of the Cip/Kip CDK...

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Hlavní autoři: Lin, Han, Hu, Guo-Xin, Dong, Lei, Dong, Qiang, Mukai, Motoko, Chen, Bing-Bing, Holsberger, Denise R., Sottas, Chantal M., Cooke, Paul S., Lian, Qing-Quan, Li, Xiao-Kun, Ge, Ren-Shan
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for the Study of Reproduction, Inc. 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804804/
https://ncbi.nlm.nih.gov/pubmed/19211806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.074229
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