ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma

BACKGROUND: Cancer cells display widespread changes in DNA methylation that may lead to genetic instability by global hypomethylation and aberrant silencing of tumor suppressor genes by focal hypermethylation. In turn, altered DNA methylation patterns have been used to identify putative tumor suppre...

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Hlavní autoři: Götze, Silke, Feldhaus, Valeska, Traska, Thilo, Wolter, Marietta, Reifenberger, Guido, Tannapfel, Andrea, Kuhnen, Cornelius, Martin, Dirk, Müller, Oliver, Sievers, Sonja
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804712/
https://ncbi.nlm.nih.gov/pubmed/20017917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-447
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