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Differentiation of an interleukin 3-dependent precursor B-cell clone into immunoglobulin-producing cells in vitro.

Precursors to B-cell lines with immunoglobulin genes in the germ-line context have been shown to be capable of generating mature B cells in vivo. We report here that an interleukin 3-dependent precursor B-cell line, LyD9, differentiated in vitro into mature B cells, producing IgM and IgG by cocultur...

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Autors principals: Kinashi, T, Inaba, K, Tsubata, T, Tashiro, K, Palacios, R, Honjo, T
Format: Artigo
Idioma:Inglês
Publicat: 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC280452/
https://ncbi.nlm.nih.gov/pubmed/3260035
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