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Reversal of the metastatic phenotype in Lewis lung carcinoma cells after transfection with syngeneic H-2Kb gene.

High metastatic clones of the murine 3LL carcinoma express greatly reduced levels of H-2Kb major histocompatibility complex class I antigens, while low metastatic clones of the same tumor express high levels of H-2Kb. Induced expression of this antigen after transfection with the H-2Kb gene resulted...

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Bibliographic Details
Main Authors: Plaksin, D, Gelber, C, Feldman, M, Eisenbach, L
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC280450/
https://ncbi.nlm.nih.gov/pubmed/3380801
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