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The Caenorhabditis elegans Germ Line Regulates Distinct Signaling Pathways to Control Lifespan and Innate Immunity

The relationship between the mechanisms that control an organism's lifespan and its ability to respond to environmental challenges are poorly understood. In Caenorhabditis elegans, an insulin-like signaling pathway modulates lifespan and the innate immune response to bacterial pathogens via a c...

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Autori principali: Alper, Scott, McElwee, Matthew K., Apfeld, Javier, Lackford, Brad, Freedman, Jonathan H., Schwartz, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804340/
https://ncbi.nlm.nih.gov/pubmed/19923212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.057323
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