Interaction of Insulin-like Growth Factor-binding Protein-3 and BAX in Mitochondria Promotes Male Germ Cell Apoptosis

Germ cell apoptosis is crucial for spermatogenesis and can be triggered by various stimuli, including intratesticular hormone deprivation. This study proposes a role for insulin-like growth factor binding protein-3 (IGFBP-3) in male germ cell apoptosis. Groups of adult Sprague-Dawley male rats recei...

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Autors principals: Jia, Yue, Lee, Kuk-Wha, Swerdloff, Ronald, Hwang, David, Cobb, Laura J., Sinha Hikim, Amiya, Lue, Yan He, Cohen, Pinchas, Wang, Christina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804330/
https://ncbi.nlm.nih.gov/pubmed/19887447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046847
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