Dimerization Is Essential for 14-3-3ζ Stability and Function in Vivo

Members of the conserved 14-3-3 protein family spontaneously self-assemble as homo- and heterodimers via conserved sequences in the first four (αA-αD) of the nine helices that comprise them. Dimeric 14-3-3s bind conserved motifs in diverse protein targets involved in multiple essential cellular proc...

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Bibliographic Details
Main Authors: Messaritou, Georgia, Grammenoudi, Sofia, Skoulakis, Efthimios M. C.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804327/
https://ncbi.nlm.nih.gov/pubmed/19920133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045989
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