YybT Is a Signaling Protein That Contains a Cyclic Dinucleotide Phosphodiesterase Domain and a GGDEF Domain with ATPase Activity

The cyclic dinucleotide c-di-GMP synthesized by the diadenylate cyclase domain was recently discovered as a messenger molecule for signaling DNA breaks in Bacillus subtilis. By searching bacterial genomes, we identified a family of DHH/DHHA1 domain proteins (COG3387) that co-occur with a subset of t...

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Bibliographic Details
Main Authors: Rao, Feng, See, Rui Yin, Zhang, Dongwei, Toh, Delon Chengxu, Ji, Qiang, Liang, Zhao-Xun
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Enzyme Catalysis and Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804195/
https://ncbi.nlm.nih.gov/pubmed/19901023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.040238
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