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Bordetella Adenylate Cyclase Toxin Promotes Calcium Entry into Both CD11b(+) and CD11b(−) Cells through cAMP-dependent L-type-like Calcium Channels

Adenylate cyclase toxin (ACT), a 200 kDa protein, is an essential virulence factor for Bordetella pertussis, the bacterium that causes whooping cough. ACT is a member of the pore-forming RTX (repeats-in-toxin) family of proteins that share a characteristic calcium-binding motif of Gly- and Asp-rich...

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Detalhes bibliográficos
Main Authors: Martín, César, Gómez-Bilbao, Geraxane, Ostolaza, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804183/
https://ncbi.nlm.nih.gov/pubmed/19875442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003491
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