Wnt/β-Catenin and Retinoic Acid Receptor Signaling Pathways Interact to Regulate Chondrocyte Function and Matrix Turnover

Activation of the Wnt/β-catenin and retinoid signaling pathways is known to tilt cartilage matrix homeostasis toward catabolism. Here, we investigated possible interactions between these pathways. We found that all-trans-retinoic acid (RA) treatment of mouse epiphyseal chondrocytes in culture did in...

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Detalhes bibliográficos
Main Authors: Yasuhara, Rika, Yuasa, Takahito, Williams, Julie A., Byers, Stephen W., Shah, Salim, Pacifici, Maurizio, Iwamoto, Masahiro, Enomoto-Iwamoto, Motomi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804179/
https://ncbi.nlm.nih.gov/pubmed/19858186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053926
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