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Transient Activation of Wnt/β-Catenin Signaling Induces Abnormal Growth Plate Closure and Articular Cartilage Thickening in Postnatal Mice

Wnt/β-catenin signaling is required for skeletal development and organization and for function of the growth plate and articular cartilage. To further clarify these roles and their possible pathophysiological importance, we created a new transgenic mouse model in which Wnt/β-catenin signaling can be...

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Autors principals: Yuasa, Takahito, Kondo, Naoki, Yasuhara, Rika, Shimono, Kengo, Mackem, Susan, Pacifici, Maurizio, Iwamoto, Masahiro, Enomoto-Iwamoto, Motomi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774063/
https://ncbi.nlm.nih.gov/pubmed/19815716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.081173
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