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HECT Domain-containing E3 Ubiquitin Ligase Nedd4 Interacts with and Ubiquitinates Sprouty2

Sprouty (Spry) proteins are important regulators of receptor tyrosine kinase signaling in development and disease. Alterations in cellular Spry content have been associated with certain forms of cancers and also in cardiovascular diseases. Thus, understanding the mechanisms that regulate cellular Sp...

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Detalhes bibliográficos
Main Authors: Edwin, Francis, Anderson, Kimberly, Patel, Tarun B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804172/
https://ncbi.nlm.nih.gov/pubmed/19864419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.030882
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