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Recognition of Adenosine Residues by the Active Site of Poly(A)-specific Ribonuclease
Poly(A)-specific ribonuclease (PARN) is a mammalian 3′-exoribonuclease that degrades poly(A) with high specificity. To reveal mechanisms by which poly(A) is recognized by the active site of PARN, we have performed a kinetic analysis using a large repertoire of trinucleotide substrates. Our analysis...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804161/ https://ncbi.nlm.nih.gov/pubmed/19901024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.043893 |
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