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TGFβ1 Inhibits Ca(2+)-Calcineurin-Mediated Activation in Thymocytes

TGFβ1 is a polypeptide growth modulatory and differentiation factor involved in many biological processes including immune homeostasis and self-tolerance. Tgfb1 knockout mice die around weaning age due to severe inflammation in most major organ systems, but the mechanism underlying this disease is n...

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Main Authors: Bommireddy, Ramireddy, Ormsby, Ilona, Yin, Moying, Boivin, Gregory P., Babcock, George F., Doetschman, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804068/
https://ncbi.nlm.nih.gov/pubmed/12646629
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