NMDA Receptor Phosphorylation at a Site Affected in Schizophrenia Controls Synaptic and Behavioral Plasticity

Phosphorylation of the NR1 subunit of NMDA receptors (NMDARs) at serine (S) 897 is markedly reduced in schizophrenia patients. However, the role of NR1 S897 phosphorylation in normal synaptic function and adaptive behaviors are unknown. To address these questions, we generated mice in which the NR1...

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Detalhes bibliográficos
Main Authors: Li, Bo, Devidze, Nino, Barengolts, Denis, Prostak, Naseem, Sphicas, Eleana, Apicella, Alfonso J., Malinow, Roberto, Emamian, Effat S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804063/
https://ncbi.nlm.nih.gov/pubmed/19776282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2109-09.2009
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