Synthetic peptides as substrates and inhibitors of a retroviral protease.
Processing of the gag and pol gene precursor proteins of retroviruses is essential for infectivity and is directed by a viral protease that is itself included in one of these precursors. We demonstrate here that small synthetic peptides can be used as both model substrates and inhibitors to investig...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1988
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280391/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2837759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4185 |
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