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Synthetic peptides as substrates and inhibitors of a retroviral protease.

Processing of the gag and pol gene precursor proteins of retroviruses is essential for infectivity and is directed by a viral protease that is itself included in one of these precursors. We demonstrate here that small synthetic peptides can be used as both model substrates and inhibitors to investig...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kotler, M, Katz, R A, Danho, W, Leis, J, Skalka, A M
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1988
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280391/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2837759/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4185
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