Effects of the MEK Inhibitor, SL-327, on Rewarding, Motor- and Cellular-Activating Effects of D-Amphetamine and SKF-82958, and their Augmentation by Food Restriction in Rat

RATIONALE: Food restriction (FR) enhances learned and unlearned behavioral responses to drugs of abuse and increases D-1 dopamine (DA) receptor-mediated activation of ERK 1/2 MAP kinase in nucleus accumbens (NAc). While a role has been established for ERK signaling in drug-mediated associative learn...

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Hlavní autoři: Carr, Kenneth D., de Vaca, Soledad Cabeza, Sun, Yanjie, Chau, Lily S., Pan, Yan, Cruz, Julie Dela
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803695/
https://ncbi.nlm.nih.gov/pubmed/18766328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-008-1313-6
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