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Effects of the MEK Inhibitor, SL-327, on Rewarding, Motor- and Cellular-Activating Effects of D-Amphetamine and SKF-82958, and their Augmentation by Food Restriction in Rat
RATIONALE: Food restriction (FR) enhances learned and unlearned behavioral responses to drugs of abuse and increases D-1 dopamine (DA) receptor-mediated activation of ERK 1/2 MAP kinase in nucleus accumbens (NAc). While a role has been established for ERK signaling in drug-mediated associative learn...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2803695/ https://ncbi.nlm.nih.gov/pubmed/18766328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-008-1313-6 |
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