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Interleukin 2-diphtheria toxin fusion protein can abolish cell-mediated immunity in vivo.

De novo expression of the interleukin 2 receptor (IL-2R) is a critical and pivotal event in initiation of an immune response. Targeting the low-affinity IL-2-binding p55 subunit of the high-affinity IL-2R with the rat anti-mouse IgM monoclonal antibody M7/20 suppresses a variety of T-cell-mediated r...

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Bibliografski detalji
Glavni autori: Kelley, V E, Bacha, P, Pankewycz, O, Nichols, J C, Murphy, J R, Strom, T B
Format: Artigo
Jezik:Inglês
Izdano: 1988
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC280344/
https://ncbi.nlm.nih.gov/pubmed/3131768
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