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Role for intracellular proteases in the processing and transport of class II HLA antigens.

Human B-lymphoblastoid cell lines (B-LCL) incubated with the protease inhibitor leupeptin accumulate complexes of class II HLA antigens with a series of Mr 21,000-23,000 basic proteins termed leupeptin-induced proteins (LIP). The appearance of class II antigen-associated LIP coincides with the disap...

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Detalhes bibliográficos
Main Authors: Blum, J S, Cresswell, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC280343/
https://ncbi.nlm.nih.gov/pubmed/3287381
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