Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

BACKGROUND: Hyperuricemia, a highly heritable trait, is a key risk factor for gout. We aimed to identify novel genes related to serum uric acid (UA) and gout. METHODS: Genome-wide association studies (GWAS) were conducted for serum UA in the Framingham Heart Study (FHS; n=7699) and the Rotterdam Stu...

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主要な著者: Dehghan, Abbas, Köttgen, Anna, Yang, Qiong, Hwang, Shih-Jen, Linda Kao, W. H., Rivadeneira, Fernando, Boerwinkle, Eric, Levy, Daniel, Hofman, Albert, Astor, Brad C., Benjamin, Emelia J., van Duijn, Cornelia M., Witteman, Jacqueline C., Coresh, Josef, Fox, Caroline S.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803340/
https://ncbi.nlm.nih.gov/pubmed/18834626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(08)61343-4
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