Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

BACKGROUND: Hyperuricemia, a highly heritable trait, is a key risk factor for gout. We aimed to identify novel genes related to serum uric acid (UA) and gout. METHODS: Genome-wide association studies (GWAS) were conducted for serum UA in the Framingham Heart Study (FHS; n=7699) and the Rotterdam Stu...

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Autores principales: Dehghan, Abbas, Köttgen, Anna, Yang, Qiong, Hwang, Shih-Jen, Linda Kao, W. H., Rivadeneira, Fernando, Boerwinkle, Eric, Levy, Daniel, Hofman, Albert, Astor, Brad C., Benjamin, Emelia J., van Duijn, Cornelia M., Witteman, Jacqueline C., Coresh, Josef, Fox, Caroline S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803340/
https://ncbi.nlm.nih.gov/pubmed/18834626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(08)61343-4
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