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RalA Suppresses Early Stages of Ras-Induced Squamous Cell Carcinoma Progression

Ras proteins activate Raf and PI-3 kinases, as well as exchange factors for RalA and RalB GTPases. Many previous studies have reported that the Ral signaling cascade contributes positively to Ras-mediated oncogenesis. Here, utilizing a bioengineered tissue model of early steps in Ras-induced human s...

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Bibliografische gegevens
Hoofdauteurs: Sowalsky, Adam G., Alt-Holland, Addy, Shamis, Yulia, Garlick, Jonathan A., Feig, Larry A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803332/
https://ncbi.nlm.nih.gov/pubmed/19802010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.307
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