Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: a prospective case-control analysis nested in the EPIC-Norfolk population study

LCAT plays a key role in the maturation of HDL, as evidenced by low HDL-cholesterol levels in carriers of deleterious mutations in LCAT. However, the role of LCAT in atherosclerosis is unclear. We set out to study this in a prospective study. Plasma LCAT levels, which strongly correlate with LCAT ac...

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Detalhes bibliográficos
Main Authors: Holleboom, A. G., Kuivenhoven, J. A., Vergeer, M., Hovingh, G. K., van Miert, J. N., Wareham, N. J., Kastelein, J. J. P., Khaw, K-T., Boekholdt, S. M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Patient-Oriented and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803244/
https://ncbi.nlm.nih.gov/pubmed/19671930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P900038-JLR200
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