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Characterization of desnutrin functional domains: critical residues for triacylglycerol hydrolysis in cultured cells
Murine desnutrin/human ATGL is a triacylglycerol (TAG) hydrolase with a predicted catalytic dyad within an α-β hydrolase fold in the N-terminal region. In humans, mutations resulting in C-terminal truncation cause neutral lipid storage disease with myopathy. To identify critical functional domains,...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2803232/ https://ncbi.nlm.nih.gov/pubmed/19692632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M000729 |
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