The NLRP3 Inflammasome Mediates in vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

NLR genes mediate host immunity to various pathogenic stimuli. However, in vivo evidence for NLR involvement in viral sensing has not been widely investigated and remains controversial. As an ultimate test of the physiologic role of NLRP3 during RNA viral infection, this work explores the in vivo ro...

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Hlavní autoři: Allen, Irving C., Scull, Margaret A., Moore, Chris B., Holl, Eda K., McElvania-TeKippe, Erin, Taxman, Debra J., Guthrie, Elizabeth H., Pickles, Raymond J., Ting, Jenny P.-Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803103/
https://ncbi.nlm.nih.gov/pubmed/19362020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.02.005
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