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GITR blockade facilitates T-reg mediated allograft survival
BACKGROUND: Many models of transplant tolerance have been found to depend upon the induction of regulatory T cells (T-regs). Innate immune signals are known to down-regulate T-regs thereby augmenting immunity by abrogating regulatory T cell function. Such signals may also provide a barrier to transp...
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Main Authors: | , , , , , , , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
2009
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2803064/ https://ncbi.nlm.nih.gov/pubmed/19935370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181ba6f85 |
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