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Adenosine A3 receptor deficiency exerts unanticipated protective effects on the pressure overloaded left ventricle

BACKGROUND: Endogenous adenosine can protect the overloaded heart against the development of hypertrophy and heart failure, but the contribution of A(1) receptors (A(1)R) and A(3) receptors(A(3)R) is not known. METHODS AND RESULTS: To test the hypothesis A(1)R and A(3)R can protect the heart against...

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Autores principales: Lu, Zhongbing, Fassett, John, Xu, Xin, Hu, Xinli, Zhu, Guangshuo, French, Joel, Zhang, Ping, Schnermann, Jurgen, Bache, Robert J, Chen, Yingjie
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803050/
https://ncbi.nlm.nih.gov/pubmed/18838560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.788307
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