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Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo.

Exposure of 3T3-L1 cells to insulin stimulates a soluble, serine(threonine)-specific protein kinase that phosphorylates microtubule-associated protein 2 (MAP-2) in vitro. The enzyme, termed MAP kinase, was isolated from insulin-treated or control cells radiolabeled with 32Pi. A 40-kDa phosphoprotein...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ray, L B, Sturgill, T W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280296/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3287375/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.3753
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