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Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo.

Exposure of 3T3-L1 cells to insulin stimulates a soluble, serine(threonine)-specific protein kinase that phosphorylates microtubule-associated protein 2 (MAP-2) in vitro. The enzyme, termed MAP kinase, was isolated from insulin-treated or control cells radiolabeled with 32Pi. A 40-kDa phosphoprotein...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ray, L B, Sturgill, T W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC280296/
https://ncbi.nlm.nih.gov/pubmed/3287375
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