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Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo.
Exposure of 3T3-L1 cells to insulin stimulates a soluble, serine(threonine)-specific protein kinase that phosphorylates microtubule-associated protein 2 (MAP-2) in vitro. The enzyme, termed MAP kinase, was isolated from insulin-treated or control cells radiolabeled with 32Pi. A 40-kDa phosphoprotein...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3287375/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.3753 |
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