Role of Insulin-Like Growth Factor-Binding Protein 5 (IGFBP5) in Organismal and Pancreatic β-Cell Growth

A family of IGF-binding proteins (IGFBP) exerts biological actions both dependent on and independent of IGF-I. A major effector of the insulin/IGF-I signaling pathway, the serine/threonine protein kinase Akt, mediates cellular processes such as glucose uptake, protein synthesis, cell survival, and g...

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Bibliographic Details
Main Authors: Gleason, Catherine E., Ning, Yun, Cominski, Tara P., Gupta, Rana, Kaestner, Klaus H., Pintar, John E., Birnbaum, Morris J.
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802899/
https://ncbi.nlm.nih.gov/pubmed/19897600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0167
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