Complement activation pathways in murine immune complex-induced arthritis and in C3a and C5a generation in vitro

The alternative pathway (AP) of complement alone is capable of mediating immune complex-induced arthritis in the collagen antibody-induced arthritis (CAIA) model in mice. Whether the classical pathway (CP) or lectin pathway (LP) alone can mediate CAIA is not known. Using mice genetically deficient i...

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Detalhes bibliográficos
Main Authors: Banda, N K, Levitt, B, Wood, A K, Takahashi, K, Stahl, G L, Holers, V M, Arend, W P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Animal Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802700/
https://ncbi.nlm.nih.gov/pubmed/19843088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.04035.x
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