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Single Nucleotide Polymorphisms of Gemcitabine Metabolic Genes and Pancreatic Cancer Survival and Drug Toxicity
PURPOSE: To demonstrate whether single nucleotide polymorphisms (SNPs) of drug metabolic genes were associated with toxicity of gemcitabine-based chemoradiotherapy and overall survival (OS) of patients with pancreatic cancer. EXPERIMENTAL DESIGN: We evaluated 17 SNPs of the CDA, dCK, DCTP, RRM1, hCN...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802655/ https://ncbi.nlm.nih.gov/pubmed/20028759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1555 |
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