Regional Differential Effects of the Novel Histamine H(3) Receptor Antagonist 6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on Histamine Release in the Central Nervous System of Freely Moving Rats

After oral administration, the nonimidazole histamine H(3) receptor antagonist, 6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254), increased histamine release from the tuberomammillary nucleus, where all histaminergic somata are lo...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Giannoni, Patrizia, Medhurst, Andrew D., Passani, Maria Beatrice, Giovannini, Maria Grazia, Ballini, Chiara, Corte, Laura Della, Blandina, Patrizio
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2010
Sujets:
Neuropharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802467/
https://ncbi.nlm.nih.gov/pubmed/19815811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.158444
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires