Analysis of genetic variability and mapping of point mutations in influenza virus by the RNase A mismatch cleavage method.

We have applied the RNase A mismatch cleavage method to analyze genetic variability in RNA viruses by using influenza virus as a model system. Uniformly labeled RNA probes synthesized from a cloned hemagglutinin gene of a given viral strain were hybridized to RNA isolated from other strains of chara...

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Hlavní autoři: Lopez-Galindez, C, Lopez, J A, Melero, J A, de la Fuente, L, Martinez, C, Ortin, J, Perucho, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1988
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC280244/
https://ncbi.nlm.nih.gov/pubmed/3368463
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