Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01–08)

Platelet-derived growth factor (PDGF) and its receptors (PDGFR) are frequently coexpressed in meningiomas, potentially contributing to their pathogenesis. The North American Brain Tumor Consortium conducted a phase II study to evaluate the therapeutic potential of imatinib mesylate (Gleevec), a PDGF...

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Détails bibliographiques
Auteurs principaux: Wen, Patrick Y., Yung, W.K. Alfred, Lamborn, Kathleen R., Norden, Andrew D., Cloughesy, Timothy F., Abrey, Lauren E., Fine, Howard A., Chang, Susan M., Robins, H. Ian, Fink, Karen, DeAngelis, Lisa M., Mehta, Minesh, Di Tomaso, Emmanuelle, Drappatz, Jan, Kesari, Santosh, Ligon, Keith L., Aldape, Ken, Jain, Rakesh K., Stiles, Charles D., Egorin, Merrill J., Prados, Michael D.
Format: Artigo
Langue:Inglês
Publié: Duke University Press 2009
Sujets:
Clinical Investigations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802405/
https://ncbi.nlm.nih.gov/pubmed/19293394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2009-010
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