Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01–08)

Platelet-derived growth factor (PDGF) and its receptors (PDGFR) are frequently coexpressed in meningiomas, potentially contributing to their pathogenesis. The North American Brain Tumor Consortium conducted a phase II study to evaluate the therapeutic potential of imatinib mesylate (Gleevec), a PDGF...

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Hauptverfasser: Wen, Patrick Y., Yung, W.K. Alfred, Lamborn, Kathleen R., Norden, Andrew D., Cloughesy, Timothy F., Abrey, Lauren E., Fine, Howard A., Chang, Susan M., Robins, H. Ian, Fink, Karen, DeAngelis, Lisa M., Mehta, Minesh, Di Tomaso, Emmanuelle, Drappatz, Jan, Kesari, Santosh, Ligon, Keith L., Aldape, Ken, Jain, Rakesh K., Stiles, Charles D., Egorin, Merrill J., Prados, Michael D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Duke University Press 2009
Schlagworte:
Clinical Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802405/
https://ncbi.nlm.nih.gov/pubmed/19293394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2009-010
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