Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01–08)

Platelet-derived growth factor (PDGF) and its receptors (PDGFR) are frequently coexpressed in meningiomas, potentially contributing to their pathogenesis. The North American Brain Tumor Consortium conducted a phase II study to evaluate the therapeutic potential of imatinib mesylate (Gleevec), a PDGF...

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Main Authors: Wen, Patrick Y., Yung, W.K. Alfred, Lamborn, Kathleen R., Norden, Andrew D., Cloughesy, Timothy F., Abrey, Lauren E., Fine, Howard A., Chang, Susan M., Robins, H. Ian, Fink, Karen, DeAngelis, Lisa M., Mehta, Minesh, Di Tomaso, Emmanuelle, Drappatz, Jan, Kesari, Santosh, Ligon, Keith L., Aldape, Ken, Jain, Rakesh K., Stiles, Charles D., Egorin, Merrill J., Prados, Michael D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Duke University Press 2009
Ábhair:
Clinical Investigations
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802405/
https://ncbi.nlm.nih.gov/pubmed/19293394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2009-010
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