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Spectrum of spontaneous mutation at the APRT locus of Chinese hamster ovary cells: an analysis at the DNA sequence level.

The spectrum of spontaneous mutation of an endogenous mammalian cell gene has been determined at the DNA sequence level. Thirty independent spontaneous APRT- mutations were cloned and subsequently completely sequenced. Twenty-seven contained single base substitutions. Of these, 22 were G.C to A.T tr...

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Bibliografische gegevens
Hoofdauteurs: de Jong, P J, Grosovsky, A J, Glickman, B W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1988
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC280239/
https://ncbi.nlm.nih.gov/pubmed/3368459
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