Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model

BACKGROUND: We have previously shown that small molecule PDGF receptor tyrosine kinase inhibitors (RTKI) can drastically attenuate radiation-induced pulmonary fibrosis if the drug administration starts at the time of radiation during acute inflammation with present but limited effects against acute...

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Main Authors: Li, Minglun, Abdollahi, Amir, Gröne, Hermann-Josef, Lipson, Kenneth E, Belka, Claus, Huber, Peter E
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802357/
https://ncbi.nlm.nih.gov/pubmed/20025728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-4-66
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