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Developmental regulation of an insulin-degrading enzyme from Drosophila melanogaster.

The precise mechanism by which insulin is degraded in mammalian cells is not presently known. Several lines of evidence suggest that degradation is initiated by a specific nonlysosomal insulin-degrading enzyme (IDE). The potential importance of this insulin protease is illustrated by the fact that t...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Stoppelli, M P, Garcia, J V, Decker, S J, Rosner, M R
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280233/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3130628/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.10.3469
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