12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels

BACKGROUND: Induction of 15-lipoxygenase-1 (15-LO-1) has been observed in the airways of subjects with asthma, although its physiologic role in the airways has remained largely undefined. OBJECTIVES: We sought to test the hypothesis that the mouse 15-LO-1 ortholog 12/15-LO contributes to the develop...

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Detaylı Bibliyografya
Asıl Yazarlar: Hajek, Amanda R., Lindley, Alexa R., Favoreto, Silvio, Carter, Roderick, Schleimer, Robert P., Kuperman, Douglas A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802267/
https://ncbi.nlm.nih.gov/pubmed/18692885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2008.06.021
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