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12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels
BACKGROUND: Induction of 15-lipoxygenase-1 (15-LO-1) has been observed in the airways of subjects with asthma, although its physiologic role in the airways has remained largely undefined. OBJECTIVES: We sought to test the hypothesis that the mouse 15-LO-1 ortholog 12/15-LO contributes to the develop...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802267/ https://ncbi.nlm.nih.gov/pubmed/18692885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2008.06.021 |
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