Oral Bioavailability Enhancement of Exemestane from Self-Microemulsifying Drug Delivery System (SMEDDS)

Limited aqueous solubility of exemestane leads to high variability in absorption after oral administration. To improve the solubility and bioavailability of exemestane, the self-microemulsifying drug delivery system (SMEDDS) was developed. SMEDDS comprises of isotropic mixture of natural or syntheti...

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Bibliographic Details
Main Authors: Singh, Ajeet K., Chaurasiya, Akash, Awasthi, Anshumali, Mishra, Gautam, Asati, Dinesh, Khar, Roop K., Mukherjee, Rama
Format: Artigo
Language:Inglês
Published: Springer US 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802159/
https://ncbi.nlm.nih.gov/pubmed/19609837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9281-7
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