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Histone Deacetylase Inhibitors Protect against and Mitigate the Lethality of Total-Body Irradiation in Mice

It was hypothesized that histone deacetylase (HDAC) inhibitors may increase survival after total-body irradiation (TBI) based on previous reports demonstrating that HDAC inhibitors stimulate the proliferation of bone marrow stem cells. Using the time for mice to lose 20% or more of their weight as t...

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Detalhes bibliográficos
Main Authors: Brown, Stephen L., Kolozsvary, Andrew, Liu, Jianguo, Ryu, Samuel, Kim, Jae Ho
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802131/
https://ncbi.nlm.nih.gov/pubmed/18363436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1245.1
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