Phosphoglycerate Kinase 2 (PGK2) Is Essential for Sperm Function and Male Fertility in Mice

Phosphoglycerate kinase 2 (PGK2), an isozyme that catalyzes the first ATP-generating step in the glycolytic pathway, is encoded by an autosomal retrogene that is expressed only during spermatogenesis. It replaces the ubiquitously expressed phosphoglycerate kinase 1 (PGK1) isozyme following repressio...

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Main Authors: Danshina, Polina V., Geyer, Christopher B., Dai, Qunsheng, Goulding, Eugenia H., Willis, William D., Kitto, G. Barrie, McCarrey, John R., Eddy, E.M., O'Brien, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802118/
https://ncbi.nlm.nih.gov/pubmed/19759366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.079699
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